Frequency of CYP1A1*2A polymorphisms and deletion of the GSMT1 gene in a Peruvian mestizo population

The polymorphic variants of CYP1A1 and the deletion GSTM1 are present in Peruvian mestizo population. Wild type mutated genotypes (WT/*2A *2A/ *2A) were identified, whose allele frequencies 0.31 (T allele) 0.69 (C allele), respectively; 53% with wild (+) 47% null . frequency Iquiteño emigrants was 0.72 CYP1A1*2A 25% (-); from Lima 0.67 33% (-). Hardy-Weinberg equilibrium test for studied population showed that both out balance, p > .05. presence risk polymorphism gene high, which could be indicative a phase I II metabolic imbalance this group populations, potential risks activating agents procarcinogens thus affecting incidence tumor pathologies an environmental component.